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Near equivalentChemicals

Sensitiser

A substance that, on first or repeated exposure, induces a state of hypersensitivity such that subsequent exposure to small amounts causes an allergic reaction. Respiratory and skin sensitisers require specific controls under the chemical control regimes of each framework.

Also known as

respiratory sensitiserskin sensitiser

By jurisdiction

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UK HSE

“sensitiser”Exact equivalent

COSHH 2002 regulation 2(1) defines a sensitiser as any substance or preparation which is classified as a sensitiser under the CLP Regulation. Respiratory sensitisers cause occupational asthma; skin sensitisers cause allergic contact dermatitis. COSHH requires specific control measures for sensitisers and health surveillance of exposed workers.

RegulatoryControl of Substances Hazardous to Health Regulations 2002, regulation 2(1)Source
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Irish HSA

“sensitiser”Close equivalent

The Chemical Agents Regulations 2001 and the Carcinogens and Mutagens Regulations apply to respiratory and skin sensitisers in Irish workplaces. A sensitiser is classified under EU CLP Regulation (Regulation (EC) No 1272/2008). Health surveillance is required for workers exposed to respiratory sensitisers.

Jurisdiction note: Ireland uses EU CLP classification. GB uses GB CLP (post-Brexit retained legislation). The hazard categories are aligned but are administered under separate legal instruments.
RegulatorySafety, Health and Welfare at Work (Chemical Agents) Regulations 2001; EU CLP Regulation 1272/2008Source
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US OSHA

“sensitiser”Close equivalent

OSHA classifies respiratory and skin sensitisers under the HazCom Standard (29 CFR 1910.1200 Appendix A) using GHS criteria. Sensitisers classified under HazCom require appropriate labelling, SDS sections on health hazards, and employer communication to workers. No single general standard mandates specific health surveillance for sensitiser-exposed workers.

Jurisdiction note: OSHA classification uses GHS Appendix A. Health surveillance for sensitiser-exposed workers is not universally mandated as it is under COSHH.
Regulatory29 CFR 1910.1200 Appendix ASource

Practitioner note: There is no safe exposure for an already-sensitised worker. Prevent sensitisation in the first place, because once it occurs the options narrow to removal from exposure.

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